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Final answer:The macromolecule that forms the waterproof "waxy" layer on many plants is a lipid, specifically a polymer called cutin. Other macromolecules, such as carbohydrates, proteins, and nucleic acids, serve various vital functions in living organisms.Explanation:The macromolecule that forms a waterproofing "waxy" layer on many plants, preventing water loss, is part of the class of macromolecules known as lipids. This waxy covering is commonly referred to as the cuticle and is found on the leaves, stems, and fruits of plants. The specific type of lipid typically involved in forming this barrier is called a cutin, which is a polymer of hydroxy fatty acids. Phospholipids, another type of lipid, are major components of cell membranes, but not typically part of the waxy covering on leaves.The four major classes of organic compounds that are essential for all life forms include carbohydrates, proteins, nucleic acids, and lipids. Carbohydrates serve as a vital energy source and provide structural support, whereas proteins and nucleic acids are involved in a plethora of activities, including enzyme catalysis, DNA replication, and many others. Lipids play crucial roles ranging from energy storage to forming protective barriers like the plant cuticle....