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The given DNA non‑template sequence (coding sequence) is transcribed from 3' to 5'. Use the sequence to determine the type of mutation and the type of base substitutions that apply to each scenario. Place only one statement for each scenario. 3' A T G A A G C G C T C A G T A 5' A thymine substituted for nucleotide 6 A guanine substituted for nucleotide 11 A guanine substituted for nucleotide 15
The given DNA non‑template sequence (coding sequence) is transcribed from 3' to 5'. Use the sequence to determine the type of mutation and the type of base substitutions that apply to each scenario. Place only one statement for each scenario. 3' A T G A A G C G C T C A G T A 5' A thymine substituted for nucleotide 6 A guanine substituted for nucleotide 11 A guanine substituted for nucleotide 15
Thethyminesubstituted for nucleotide 6: This is a missense mutation, resulting in a single-base substitution .A guanine substituted for nucleotide 11: This is a missense mutation, causing a single-base substitution .A guanine substituted for nucleotide 15: This is a silent mutation, leading to a single-base substitution that does not change the amino acid sequence.Scenario1: A thymine substituted for nucleotide 6Mutation Type: BasesubstitutionBase Substitution Type: Missense mutationA missense mutation is a type of base substitution that changes onecodonto another, resulting in a different amino acid being incorporated into the protein.In this scenario, the thymine substitution atnucleotide6 would change the codon TAC to TTC, which codes for a different amino acid (leucine instead of tyrosine).Scenario 2: Aguaninesubstituted for nucleotide 11Mutation Type: Base substitutionBase Substitution Type: NonsensemutationA nonsense mutation is a type of base substitution that changes a codon to a stop codon, which prematurely signals the end of protein translation.In this scenario, theguaninesubstitution at nucleotide 11 would change the codon GAG to GAA, which is a stop codon.This would result in atruncatedprotein that is likely to be nonfunctional.Scenario 3: A guanine substituted for nucleotide15Mutation Type: Base substitutionBase Substitution Type: Silent mutationAsilentmutation is a type of base substitution that changes a codon to a synonymous codon, which codes for the same amino acid.In this scenario, the guanine substitution at nucleotide 15 would change the codonCCGto CCA, which both code for the amino acidproline.Therefore, this mutation would have no effect on the protein sequence.For such a more question onthyminebrainly.com/question/14322475#SPJ3...