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Nucleic acidsare assembled in the5' to 3'direction during DNA replication. DNA replication is the process of duplication of DNA molecule.What are Nucleic acids?Nucleic acidsare the biomolecules occurring in the chemical compounds which serve as the primary information-carrying molecules in the cells. Nucleic acids play an important role in directing the process ofprotein synthesis. The two main classes of nucleic acids include deoxyribonucleic acid (DNA) and ribonucleic acid (RNA).Nucleic acidscan only be synthesized in vivo in the5′-to-3′ directionand these can be assembled in the same direction in cell, as the polymerases which assemblevarious types of new strands generally rely on the energy which is produced through breaking thenucleosidetriphosphate bondsto attach these new nucleoside monophosphates to the 3′-hydroxyl (−OH) group, through aphosphodiester bond.Learn more aboutNucleic acidshere:brainly.com/question/11309892#SPJ6...