Construct a three-step synthesis of 1,2-epoxycyclopentane from cyclopentanol by dragging the appropriate formulas into the bins. Note that each bin will hold only one item, and not all of the given reagents or structures will be used.

Question

Construct a three-step synthesis of 1,2-epoxycyclopentane from cyclopentanol by dragging the appropriate formulas into the bins. Note that each bin will hold only one item, and not all of the given reagents or structures will be used.

Accepted Answer

Answer:(1) Bromination, (2) E2 elimination and (3) epoxidationExplanation:In the first step, -OH groupin cyclopentanol isreplacedby more facile leaving groupBrby treating cyclopentanol withIn the second step,E2 elimination inpresence of strong base e.g.NaOEt/EtOHproduce cyclopenteneIn the third step, treatment of cyclopentene withmCPBAproduces 1,2-epoxycyclopentaneFull reaction scheme has been shown below...

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Construct a three-step synthesis of 1,2-epoxycyclopentane from cyclopentanol by dragging the appropriate formulas into the bins. Note that each bin will hold only one item, and not all of the given reagents or structures will be used.

Construct a three-step synthesis of 1,2-epoxycyclopentane from cyclopentanol by dragging the appropriate formulas into the bins. Note that each bin will hold only one item, and not all of the given reagents or structures will be used.